Question:

Fred, andrew, now LyndaNP, always somebody obsessively flooding this poor NG.with CROSSPOSTS!

Does lynda np really have bipolar depression?  Anyway depression is part of bipolar so I suppose it is ok for her to post to the depression group.  But it is very VERY dangerous to medicate bipolar depression the same way you medicate plain old depression. (if there is such a thing)  I say this because some doktors in research think that reoccurring depression is on the bipolar spectrum. Diana has schizoaffective disorder and you have not complained about here being over there, or have you?

Response:

I think it says a great deal. We’re looking at direct reflections back to the self appointed monopolizer of the any ngs she wishes to join. Moll

Then, you may want to check out your ISP’s TOS because lots of you are going to get reported for usenet abuse. if the self appointed monopolizer is abusing her service, report her; if not, kill file her but all of you jerks who do nothing more than repost her articles are no better than she is–in terms of signal to noise, it isn’t she who’s producing the noise. — Love is a fruit in season at all times, and within reach of every hand.                Mother Teresa http://home.gwi.net/~mdmpsyd/index.htm for mail remove PETERHOOD69

Response:

I think in this case it goes way beyond monopolizing, because the NEW  NG isnt a bipolar NG. its the much beleaguered,  alt.support. depression.medication, for sufferers of depression, that …This PARTY, suffering bipolar disorder is obsessively flooding with posts also CROSSPOSTED  to the bipolar support groups, DAILY, as in every day, she floods us with 20 NEW threads crossposted to the bipolar NG. If she was a sufferer fo depression, her doing what she is doing be monopoloizing.  But being she sufferers an entirely different disorder, while flooding sufferers of distinctly different disorder and then crossposts them too,  this is outright TROLLING. Fred, andrew, now LyndaNP, always somebody obsessively flooding this poor NG.with CROSSPOSTS! … – Hide quoted text — Show quoted text – I think it says a great deal. We’re looking at direct reflections back to the self appointed monopolizer of the any ngs she wishes to join. Moll AboutLyndaNPsXposting wrote nothing: your point is? — Love is a fruit in season at all times, and within reach of every hand.                Mother Teresa http://home.gwi.net/~mdmpsyd/index.htm for mail remove PETERHOOD69

Response:

I think it says a great deal. We’re looking at direct reflections back to the self appointed monopolizer of the any ngs she wishes to join. Moll – Hide quoted text — Show quoted text – AboutLyndaNPsXposting wrote nothing: your point is? — Love is a fruit in season at all times, and within reach of every hand.                Mother Teresa http://home.gwi.net/~mdmpsyd/index.htm for mail remove PETERHOOD69

Response:

AboutLyndaNPsXposting wrote nothing: your point is? — Love is a fruit in season at all times, and within reach of every hand.                Mother Teresa http://home.gwi.net/~mdmpsyd/index.htm for mail remove PETERHOOD69

Response:

– Hide quoted text — Show quoted text – http://pharmacology.about.com/health/pharmacology/library/weekly/aa00031 4a.htm Generic Drugs FAQ Prescription drugs can be a costly medical expense, especially for older people and those who are chronically ill. However, in the United States, each state has a law that allows pharmacists to substitute less expensive generic drugs for many brand-name products. Depending on your prescription needs, your savings could be significant. The same reasoning applies also to non-prescription, or over the counter, medications. What’s the difference between a generic and brand-name drug? The names are different, and the price of the generic drug is usually lower than that of a name-brand drug. A generic drug is called by its chemical name; a manufacturer assigns a brand name. Both generic and brand-name products have the same active ingredients. Overall, in a population, the generic drug is just as safe and effective as the brand-name drug. However, generics are not necessarily formulated in an identical manner to corresponding brand-name drugs. Because of that, there can be occasional differences in individual side-effects (nausea, for example; it may be better or worse with a generic versus a brand-name drug). There can also be occasional differences in an individual’s response to a generic drug (compared to the brand-name drug), since formulation differences can affect factors such as how much actually enters the bloodstream after oral administration. Do all drugs have generic equivalents? No. Newer drugs are protected by patents and are supplied by only one company. However, when the patent expires, other manufacturers can produce its generic version. Currently, about half the drugs on the market are available in generic form.  In addition to asking your physician or pharmacist about the availability of a specific generic drug, you can also investigate which drugs are available as generics by using our How To Find Drug Info page. How can I get generic drugs? Talk with your doctor or pharmacist. Explain that you want the most effective drug at the best price. Ask your doctor to write prescriptions for generic drugs when possible. Are there exceptions to the law? Yes. If your doctor writes on the prescription form that a specific brand-name drug is required, your pharmacist must fill the prescription as written. That is, a generic drug cannot be substituted. However, your pharmacist can talk with your doctor about the prescription. Perhaps there’s an acceptable generic drug that your doctor is not aware of. Your pharmacist can compare and evaluate generic and brand-name drugs and may be able to consult with your doctor to provide the right medication at the lowest possible price. Will my doctor automatically prescribe generic drugs? It depends on the physician. You can ask your doctor to write a prescription permitting substitution of a generic drug product when appropriate. You also can ask whether a generic product will be as effective and less costly. Or, you can request that only brand-name products be used to fill your prescriptions. Where can I get more information? See the links below. SOURCE: U.S. Federal Trade Commission; modified and some parts copied, as allowed. Information and links in this article were accurate as of the date near the title of the article. You can search this site or check New Drug Approvals or Drugs in the News for updates or more recent information. Additional InformationFeatured Articles         Other Drug Links Use the back button on your browser to return here. Better yet, bookmark this page Are Generic Drugs Appropriate Substitutes for Brand-name Drugs? – Yes From the American Council on Science and Health. A brief, but thorough, discussion. FDA Approval Process for Generic Medications An excellent explanation of a complicated process. From Stadtlander’s Pharmacy. Generic Drug Review Process The real thing, from the U.S. FDA. An interactive chart that provides an overview of how the FDA determines the safety and bioequivalence of generic drug products before approval for marketing. Generic Drugs From the Merck Manual of Medical Information Home Edition. A clearly-written chapter. Generic Pharmaceuticals: An Inside Look Excellent resource. From the Mylan Institute of Pharmacy, which is associated with generic drugs. Office of Generic Drugs From the U.S. FDA. A good starting point for detailed info. Plain Talk About Generics Very brief article, from Optimal Health. The Value of Generic Drugs Very brief, but a good read. Therapeutic Equivalence of Generic Drugs FDA letter to health practitioners. ABC News also has a story on the letter. Therapeutic Equivalence of Generic Drugs FDA response to U.S. National Association of Boards of Pharmacy. A different letter than the one above. How To Find Drug InfoDrug Manufacturer’s Web SitesNew Drug ApprovalsDrugs in the News IndexPharmacology HomeFor more information or details concerning this topic or specific drugs, try searching this web site. If you still need more info concerning individual drugs, it can usually be obtained by following the tips listed on our How To Find Drug Info page. Drug Manufacturer’s Web Sites are also a good source, especially for newer drugs when other information is less readily available. If you’ve tried and still can’t find the info you need, try posting your question on the Pharmacology Bulletin Board. I personally reply to some questions posted on the BB, but if you have a particular interest or expertise, please, feel free to reply to questions or add your comments or opinions. I regret that I can’t answer email questions, although your comments are always welcome. The Contact Information and FAQs Page is also always available. Disclaimer: The material in this Pharmacology web site is provided for education and information purposes only, and should not replace or substitute for advice from your physician or other health care professional. — LyndaNP Reality isn’t the way you wish things to be, nor the way they appear to be, but the way they actually are. – Robert J. Ringer — LyndaNP Reality isn’t the way you wish things to be, nor the way they appear to be, but the way they actually are. – Robert J. Ringer

Response:

Question:

x-no-archive: yes When I see my doctor again, I’m going to try a new inhaler.  Any suggestions from people about what ones are the best?  I need something better that I can use that won’t cause migraines. Rechelle

There are 4 beta2-agonist bronchodilator inhalers recommended by the NHLBI EPR2 national asthma guidelines; albuterol (MDI or DPI) [Ventolin] terbutaline  MDI [Breathaire] pirbuterol breath-actuated MDI [Maxair] bitolterol MDI [Tornalate] They all have similar action and side effects. Albuterol is the most popular and cheapest as its available in generic form. The asthma guidelines state that if you need to use the above rescue inhaler more than once per day, it indicates the need to increase your dose of inhaled steroids; Pulmicort Turbuhaler and Flovent MDI or DPI or the new most effective ones. Ellis — Free audio & video emails, greeting cards and forums Talkway – http://www.talkway.com – Talk more ways (sm)

Response:

you may be right about the connection between headaches and albuterol. i have had no problems with my maxair inhaler, but when i do my nebulizer those days are full of pain and suffering due to powerful headaches. and i never get headaches normally and when i do nothing can compete with these doozies.

Response:

x-no-archive: yes When I see my doctor again, I’m going to try a new inhaler.  Any suggestions from people about what ones are the best?  I need something better that I can use that won’t cause migraines. Rechelle

For bronchodilators I think Albuterol is considered one of the safest – but they all tend to have similiar side effects.  Another popular bronchodilator is terbutaline – never used it myself so I don’t know what the side effects are like.  In Canada (not sure about US) – Berotec is another bronchodilator – and that was the first bronchodilator I used (I now use albuterol) – I found the side effects to be worse with Berotec vs albuterol – but than everyone is different.  I have also used one called ProAir (Procaterol HCl Hemihydrate) for a bronchodilator – I found that it worked a little slower for me than berotec – but it worked well and the sideeffects will almost nil.  Again I am not sure if this drug is in the US or not.  I hear mention of Maxair too – not sure if that is an older bronchodilator or not. As people have alos probably told you here – it is important to be on an inhaled steroid drug (ask the doctor about this) – so you shouldn’t have to use the bronchodilator short acintg) very often.  Perhaps you are getting headaches from too frequent use of albuterol and if you use it less you might find it alright.  You might also find that Serevent (long acting bronchodilator) gives you less side-effects – though because it takes about 30 minutes to kick it  - it isn’t a replacement for a shortacting bronchodilator.  Some countries have access to formoterol which is both fast acting and long acting (I don’t think it is approved in the US though not sure about Canada).

Response:

I hear mention of Maxair too – not sure if that is an older bronchodilator or not.

Not sure how long Maxair has been around, but my son, daughter and I all three use it.(for about 5 years)  I don’t think it is one of the "older" ones though.It gives better delivery of the med. without a spacer and is breath activated. This makes it hard to take if you are to the point of not being able to breathe well enough to actuate it, but by this point you need a neb anyway.

Response:

– Hide quoted text — Show quoted text – x-no-archive:yes I’ve been lurking for about a day now and wanted to find out if anyone here has had any trouble taking Albuterol USP inhalers?  I’ve been asthmatic for several years now and was in bad shape Sunday night/Monday morning due to severe broncitis & sinus infection.  My peak flow was only 200 and I usually blow a 750.  I started the Albuterol yesterday and by last night had a severe migraine.  I was wondering if it was fluke or if I may have a problem with this.  I moved to the States from Canada and had a couple old inhalers but the dr. yesterday but me on a new one that he said was comparable.  Any advice on rescue inhalers would be greatly appreciated. Warmest regards, Rechelle

A side effect of albuterol at high dose is headache. However with a peak flow of only 27% PB, you would need a lot more than just albuterol. Most would head for the emergency room at this point. Some would try high dose inhaled steroids, like Pulmicort; the usual regimen is a burst dose of prednisone, along with albuterol. There are other rescue inhalers, like terbutaline; they’re all beta2 agonist bronchodilators; and all have similar side effects. Ellis — Free audio & video emails, greeting cards and forums Talkway – http://www.talkway.com – Talk more ways (sm)

Response:

I also had a steriod injection, and am on Prednisone for now.  After this, we’re going to look at other alternatives.  Just wanted to find out about the Albuterol. Rechelle – Hide quoted text — Show quoted text – x-no-archive:yes I’ve been lurking for about a day now and wanted to find out if anyone here has had any trouble taking Albuterol USP inhalers?  I’ve been asthmatic for several years now and was in bad shape Sunday night/Monday morning due to severe broncitis & sinus infection.  My peak flow was only 200 and I usually blow a 750.  I started the Albuterol yesterday and by last night had a severe migraine.  I was wondering if it was fluke or if I may have a problem with this.  I moved to the States from Canada and had a couple old inhalers but the dr. yesterday but me on a new one that he said was comparable.  Any advice on rescue inhalers would be greatly appreciated. Warmest regards, Rechelle A side effect of albuterol at high dose is headache. However with a peak flow of only 27% PB, you would need a lot more than just albuterol. Most would head for the emergency room at this point. Some would try high dose inhaled steroids, like Pulmicort; the usual regimen is a burst dose of prednisone, along with albuterol. There are other rescue inhalers, like terbutaline; they’re all beta2 agonist bronchodilators; and all have similar side effects. Ellis — Free audio & video emails, greeting cards and forums Talkway – http://www.talkway.com – Talk more ways (sm)

Response:

Question:

I take azmacort-3 puffs 2x a day, serevent-2 puffs 2x a day and singulair at bedtime.  I also use the  ventolin inhaler as needed(or in the nebulizer–which is not very often).  Does anyone know if any of this medication can cause insomnia? Thanks

Response:

I do not know all your medicines but I am new to singulair and finding it a little agitating, restless making. Fortunately for me another non asthma medicine I take makes me drowsy. I have a feeling that if it doesn’t go away you might look at singulair as the culprit. You know the principle of single subject testing don’t you?  To be sure, you must go off the suspected medicine, have the side effects go away, then go back on again, and have them come back, and go off again (if you can’t stand them) and have them go away. I take azmacort-3 puffs 2x a day, serevent-2 puffs 2x a day and singulair at bedtime.  I also use the  ventolin inhaler as needed(or in the nebulizer–which is not very often).  Does anyone know if any of this medication can cause insomnia? Thanks

Response:

I take azmacort-3 puffs 2x a day, serevent-2 puffs 2x a day and singulair at bedtime.  I also use the  ventolin inhaler as needed(or in the nebulizer–which is not very often).  Does anyone know if any of this medication can cause insomnia? Thanks

Bronchodilators are the asthma meds most likely to cause this symptom. It could be the Serevent. It can take some time to get used to it; I had nightmares when I 1st started taking it, which subsided after a couple of months. Some have to reduce the dose of Serevent. Albuterol could also do this, especially in nebulizer form. Each nebulizer treatment (2.5 gm albuterol) is equivalent to 10 puffs of albuterol by Metered Dose Inhaler. More info at www.rxlist.com type in name of drug. Ellis

Response:

People are so different in how they react. I have never heard that about serevent and never would have suspected it. – Hide quoted text — Show quoted text – I take azmacort-3 puffs 2x a day, serevent-2 puffs 2x a day and singulair at bedtime.  I also use the  ventolin inhaler as needed(or in the nebulizer–which is not very often).  Does anyone know if any of this medication can cause insomnia? Thanks Bronchodilators are the asthma meds most likely to cause this symptom. It could be the Serevent. It can take some time to get used to it; I had nightmares when I 1st started taking it, which subsided after a couple of months. Some have to reduce the dose of Serevent. Albuterol could also do this, especially in nebulizer form. Each nebulizer treatment (2.5 gm albuterol) is equivalent to 10 puffs of albuterol by Metered Dose Inhaler. More info at www.rxlist.com type in name of drug. Ellis

Response:

I take azmacort-3 puffs 2x a day, serevent-2 puffs 2x a day and singulair at bedtime.  I also use the  ventolin inhaler as needed(or in the nebulizer–which is not very often).  Does anyone know if any of this medication can cause insomnia? Thanks Yes, definitely…Serevent and/or ventolin. It’s after 1 am, and I am still up having taken the same meds! I’m experimenting with changing the time I take the Serevent…if I solve this problem, I’ll let you know. rec.crafts.textiles.needlework alt.support.asthma

Response:

Thanks.  I had pushed the time later as to taking the singulair, hoping that the effects of it would last longer into the following day.  But I’m assuming that taking singulair, serevent, azmacort and ventolin (if needed) at midnight is just a little to much before bedtime

– Hide quoted text — Show quoted text – Yes, definitely…Serevent and/or ventolin. It’s after 1 am, and I am still up having taken the same meds! I’m experimenting with changing the time I take the Serevent…if I solve this problem, I’ll let you know. rec.crafts.textiles.needlework alt.support.asthma

Response:

I too am on Serevent and have had trouble sleeping and also HORRIBLE nightmares for the last month. I’ve been on Serevent for a month!! And I have never had nightmares before in my life. I thought I was going crazy! But thanks to Ellis’s post I now know whats causing them!

Response:

Thanks.  I had pushed the time later as to taking the singulair, hoping that the effects of it would last longer into the following day.  But I’m assuming that taking singulair, serevent, azmacort and ventolin (if needed) at midnight is just a little to much before bedtime Recently I’ve pushed the time I take the Serevent later until just before I hit the sack. Seems I read that it peaks at 4 hours, so I’m trying to see what happens if I get to sleep before it really takes effect.  Well….worth a try I thought. Will let you know.  BTWm prednisome makes sleeping  a problem too. rec.crafts.textiles.needlework alt.support.asthma

Response:

Question:

OK, first of all, how are you functioning during the daytime, after your 5 hours?

80 % of the time I can function during the day, while feeling tired; 20 % of the time I lay in bed all day. Also, I have chronic Fatigue and I am on long term disability. Anything good happening from this medication after 7 weeks?

Yes, anxiety has become less pronounced, but still need to up the Effexor to better control my anxiety. My fear is if I up the Effexor then I will get no sleep at all. What is it being prescribed for?

Anxiety. Mike – Hide quoted text — Show quoted text – G Hello all, I have been taking Effexor XR 37.5 once a day for 7 weeks. The problem is the lack of sleep; I sleep 4 to 5 hours a night. Initially I thought this would go away once I acclimated to the medication, because that’s what happened in the past with other meds. Unfortunately this has not happened. My question is there any medication that would assist with my sleep problem, so I could get a good night sleep. This would probably be on a long term basis. Thank you to those who respond, Mike

Response:

OK, first of all, how are you functioning during the daytime, after your 5 hours?  Anything good happening from this medication after 7 weeks? What is it being prescribed for? G

– Hide quoted text — Show quoted text – Hello all, I have been taking Effexor XR 37.5 once a day for 7 weeks. The problem is the lack of sleep; I sleep 4 to 5 hours a night. Initially I thought this would go away once I acclimated to the medication, because that’s what happened in the past with other meds. Unfortunately this has not happened. My question is there any medication that would assist with my sleep problem, so I could get a good night sleep. This would probably be on a long term basis. Thank you to those who respond, Mike

Response:

Hello all, I have been taking Effexor XR 37.5 once a day for 7 weeks. The problem is the lack of sleep; I sleep 4 to 5 hours a night. Initially I thought this would go away once I acclimated to the medication, because that’s what happened in the past with other meds. Unfortunately this has not happened. My question is there any medication that would assist with my sleep problem, so I could get a good night sleep. This would probably be on a long term basis. Thank you to those who respond, Mike

Response:

talk to the doc who prescribed the Effexor?? that would be my first step. Lobo

Response:

Hello all, I have been taking Effexor XR 37.5 once a day for 7 weeks. The problem is the lack of sleep; I sleep 4 to 5 hours a night. Initially I thought this would go away once I acclimated to the medication, because that’s what happened in the past with other meds. Unfortunately this has not happened. My question is there any medication that would assist with my sleep problem, so I could get a good night sleep. This would probably be on a long term basis. Thank you to those who respond, Mike

Do you take Effexor for anxiety/panic, depression? Does it work at this low dose? Good sedating antidepressants that work also for anxiety/panic are amitriptyline (TCA) and Paxil (SSRI). Also Remeron which as a rule is somewhat less effective for anxiety disorders but does help people. Low dose ami and ditto Remeron are succesfully prescribed as  sleeping aids. Philip – Hide quoted text — Show quoted text –

Response:

Question:

– Hide quoted text — Show quoted text – Use a D.O. with caution as they do not have the same training as an M.D Margrove, I’ve heard or read that D.O.’s do have the same basic training as M.D.s, and take the same courses as medical students get in medical school. D.O.s are licensed to practice medicine in the state of California. Have you heard about any bad experiences with D.O.s? What is a D.O.? Philip (foreigner)

Doctor of Osteopathic Medicine. Developed 130 years ago by physician A.T. Still, osteopathic medicine is emerging as one of the fastest growing healthcare professions in the U.S. Osteopathic medicine brings a unique philosophy to traditional medicine. With a strong emphasis on the inter-relationship of the body’s nerves, muscles, bones and organs, doctors of osteopathic medicine, or D.O.s, apply the philosophy of treating the whole person to the prevention, diagnosis and treatment of illness, disease and injury. http://www.osteopathic.org — The charter is available at:

Question:

Hi, The best meds against BPD/Depression are supposedly the MAOi’s. However, they tend to cause weight gain (Parnate less than Nardil). There are *some* foods you can’t eat while on them, but they are not your typical binge foods (you can’t eat aged cheese and drink red wine, for example, but chocolate is out, too).  But if you have weight issues, you might want to avoid meds that might lead to weight gain. As to your bulimia: Prozac at higher doses is approved as a treatment against bulimia (I am a recovering bulimic and on 60mg Prozac).  There has been one study done decades back on the TCA’s isipramine/desipramine and their effect on preventing binges: for me that is completely true!  For most people they lead to weight gain. Total opposite for me.  I am on only 100mg of desipramine as Prozac raises the plasma level of all TCA’s.  And one of the best drugs against bingeing is Topamax, an anti-convulsant, which is right now undergoing clinical trials to be approved as mood stabilizer (it kicks ass as a mood stabilizer) and there are some trials going on at some universities (I forgot where), where they are testing it’s effectiveness as an anti-bingeing drug.  I haven’t even had the thought/urge/desire to binge while on it.  I don’t think I physically could binge while on Topamax, it’s hard to describe.  I am on 200mg. Maybe you could talk to your doctor about replacing the mini dose ofRisperdal with Topamax (start out slowly – 25mg once a day, then after a few days 25mg twice a day etc., or it will knock you out).  It should calm you down and relieve anxiety and freaky thinking as well as Risperdal.  You might not even need the Trazodone anymore. For me, the tricyclic/Prozac combo has been the only thing to lift me out of my depression.  It’s worth asking about it.  Do you have prescription drug insurance?  If not, e-mail me if you go on Prozac or Topamax, ok?  I might have some info for you… All the best, Elgin — "Come what come may time and hour runs through the roughest day." Shakespeare, Macbeth. — "Come what come may time and hour runs through the roughest day." Shakespeare, Macbeth. Sent via Deja.com http://www.deja.com/ Before you buy.

Response:

If you are still in your active phase of bulimia, Wellbutrin is highly unindicated, as it will increase your risk for seizures by quite a bit (bulimia, of course, increases your risk for seizures, too, as I hope you know).  If you try Wellbutrin, are in recovery from bulimia and are on an anti-convulsant/mood-stabilizer there should be no problem… Elgin In article <39B9DE4A.C75B6…@home.com

,

  Heather <h…@home.com

wrote:

– Hide quoted text — Show quoted text -

Effexor should work at least a little.  I know what you mean about feeling like a pharmacy.  I’m on Effexor XR (150 mg twice a day), clozapine (1.5 mg three times a day), Olanzapine (7.5 mg twice a day) and up until a week ago, I was also on Ritalin slow release 20 mg a day.  After I had a seizure last week ( first time I had one & in Superstore of all places…how embarassing!!!)  Anyway, they took me

off

the Ritalin since then & now I can’t concentrate worth shit!  I can relate to what you’re feeling with nothing working, I feel the same

way,

& I’ve been on almost every drug possible over the last 10 years.

Have

you tried Wellbutrin?  If it’s weight you’re worried about, it does

help

to suppress your appetite & is somewhat of a stimulant to your system, talk to your doc first to see if it’s right for you.  It’s worth a

shot.

Good Luck to you. Heather marcel…@my-deja.com wrote: I’m on 225 mg of effexor for depression, 1.5 mg Risperdal for

anxiety

and mood swings, 150 mg. Trazadone for insomnia. I feel like a

pharmacy.

unfortunately none of it seems to be workig at an optimal level. I

am

still hideously depressed and moody as all hell. My anxiety is down, but I still have occassional panic attacks. The only thing tha is working as well as it could is the Trazadone–that stuff puts me

OUT.

 I’ve heard that tricyclic, or maybe it was MAIO type anti-

depressants

are actually more effective on people with BPD than the newer generations like Prozac or Effexor. Does anyone know anything about this. Unfortunately, I know I can’t take an MAIO because i’m bulimic nad prone to impulsive eating binges, and there are many things you can’t eat on them.  All I know, though, is that my anti-depressant

is

NOT working, and i’ve given it a fair trail–nearly 2 months.  IT seems like I will be in emotional pain forever, with no relief. Also, my bulimic symptoms are not improving. Does anyone know of amedication that will target that? –marcella Sent via Deja.com http://www.deja.com/ Before you buy.

— "Come what come may time and hour runs through the roughest day." Shakespeare, Macbeth. Sent via Deja.com http://www.deja.com/ Before you buy.

Response:

Effexor should work at least a little.  I know what you mean about feeling like a pharmacy.  I’m on Effexor XR (150 mg twice a day), clozapine (1.5 mg three times a day), Olanzapine (7.5 mg twice a day) and up until a week ago, I was also on Ritalin slow release 20 mg a day.  After I had a seizure last week ( first time I had one & in Superstore of all places…how embarassing!!!)  Anyway, they took me off the Ritalin since then & now I can’t concentrate worth shit!  I can relate to what you’re feeling with nothing working, I feel the same way, & I’ve been on almost every drug possible over the last 10 years.  Have you tried Wellbutrin?  If it’s weight you’re worried about, it does help to suppress your appetite & is somewhat of a stimulant to your system, talk to your doc first to see if it’s right for you.  It’s worth a shot. Good Luck to you. Heather – Hide quoted text — Show quoted text -marcel…@my-deja.com wrote:

I’m on 225 mg of effexor for depression, 1.5 mg Risperdal for anxiety and mood swings, 150 mg. Trazadone for insomnia. I feel like a pharmacy. unfortunately none of it seems to be workig at an optimal level. I am still hideously depressed and moody as all hell. My anxiety is down, but I still have occassional panic attacks. The only thing tha is working as well as it could is the Trazadone–that stuff puts me OUT.  I’ve heard that tricyclic, or maybe it was MAIO type anti-depressants are actually more effective on people with BPD than the newer generations like Prozac or Effexor. Does anyone know anything about this. Unfortunately, I know I can’t take an MAIO because i’m bulimic nad prone to impulsive eating binges, and there are many things you can’t eat on them.  All I know, though, is that my anti-depressant is NOT working, and i’ve given it a fair trail–nearly 2 months.  IT seems like I will be in emotional pain forever, with no relief. Also, my bulimic symptoms are not improving. Does anyone know of amedication that will target that? –marcella Sent via Deja.com http://www.deja.com/ Before you buy.

Response:

I’m on 225 mg of effexor for depression, 1.5 mg Risperdal for anxiety and mood swings, 150 mg. Trazadone for insomnia. I feel like a pharmacy. unfortunately none of it seems to be workig at an optimal level. I am still hideously depressed and moody as all hell. My anxiety is down, but I still have occassional panic attacks. The only thing tha is working as well as it could is the Trazadone–that stuff puts me OUT.  I’ve heard that tricyclic, or maybe it was MAIO type anti-depressants are actually more effective on people with BPD than the newer generations like Prozac or Effexor. Does anyone know anything about this. Unfortunately, I know I can’t take an MAIO because i’m bulimic nad prone to impulsive eating binges, and there are many things you can’t eat on them.  All I know, though, is that my anti-depressant is NOT working, and i’ve given it a fair trail–nearly 2 months.  IT seems like I will be in emotional pain forever, with no relief. Also, my bulimic symptoms are not improving. Does anyone know of amedication that will target that? –marcella Sent via Deja.com http://www.deja.com/ Before you buy.

Response:

Question:

Does anyone have any experience with imipramine? 1)  What are the side effects?  Does it cause impotence the way practically all other anti-depressants do?   2)  How effective is it in treating depression? 3)  How different is it from other common drugs such as prozac, effexor, etc.? 4)  Does it have any lethal potential (will it kill a person if they OD on it in large doses)?  Many years ago, I made an unsucessful suicide attempt, and I dont want the temptation to be there if I ever get to that state again. 5)  Is does it have any addictive potential, like some meds can (i.e. you need more and more of it to get the same effect)? I presume in a group like this, many of you are currently on (or have been on) imiprimine.  I just need to get as much info as possible on, since this one of the drugs my doc has mentioned as a possibility for me.  Of course, ive asked him these questions also, but I just want to get another perspective. I’d appreciate any input from anyone out there– thanks advance allegro

Response:

Does anyone have any experience with imipramine?

Not I. Tofranil, haven’t tried it. 1)  What are the side effects?  Does it cause impotence the way practically all other anti-depressants do?  

http://www.mentalhealth.com/drug/p30-t03.html 2)  How effective is it in treating depression?

About as good as any. Actually, it’s frequently used in comparison studies. 3)  How different is it from other common drugs such as prozac, effexor, etc.?

It’s a tricyclic, kind of like a shotgun. Does a lot of stuff, that’s why the scary side effects. Meds like Prozac do less in the body and so have fewer and less frequently occurring (within a population) side effects. 4)  Does it have any lethal potential (will it kill a person if they OD on it in large doses)?  Many years ago, I made an unsucessful suicide attempt, and I dont want the temptation to be there if I ever get to that state again.

Maybe you should ask for an SSRI. All tricyclics are a little dangerous. 5)  Is does it have any addictive potential, like some meds can (i.e. you need more and more of it to get the same effect)?

None at all. If you click on the Research link at Internet Mental Health you can get a ton of abstracts. Researchers seem to like using imipramine.

Response:

I recently started taking Imipramine.  I’m up to 150Mg/day.  I’ve been on virtually all of the newer anti-depressants, so this is kind of my last hope. I can tell you this much, the newer ADs are no more effective than the older ones, such as the Tricyclics and MAOIs. As far as side effects go, I’m experiencing dry mouth and constipation.  Imipramine seems no worse than ADs like Prozac, Paxil, Serzone, Effexor, etc.  In fact, some of these newer ADs had more side effects.  Paxil, in particular, was the hardest drug to get off of.  Even though I weened off of it slowly, I experienced painful withdrawals, such as migraines, that lasted well over a month. From what I’ve read, one can OD on Imipramine, but so can one on Aspirin.  Also, it’s not addictive. I say it’s worth a try.  I mean, these newer ADs are being marketed heavily (whereas Imipramine is generic and inexpensive) and this is influencing doctors and patients.  But again, I have yet to read any studies that show Imipramine to be less effective. Does anyone have any experience with imipramine? 1)  What are the side effects?  Does it cause impotence the way practically all other anti-depressants do? 2)  How effective is it in treating depression? 3)  How different is it from other common drugs such as prozac, effexor, etc.? 4)  Does it have any lethal potential (will it kill a person if they OD on it in large doses)?  Many years ago, I made an unsucessful

suicide attempt, and I – Hide quoted text — Show quoted text – dont want the temptation to be there if I ever get to that state again. 5)  Is does it have any addictive potential, like some meds can (i.e. you need more and more of it to get the same effect)? I presume in a group like this, many of you are currently on (or have been on) imiprimine.  I just need to get as much info as possible on, since this one of the drugs my doc has mentioned as a possibility for me.  Of course, ive asked him these questions also, but I just want to get another perspective. I’d appreciate any input from anyone out there– thanks advance allegro

Before you buy.

Response:

Question:

Maybe it’s me on effexor withdrawal, but the proliferation of these multiple threads sucks.  Is there a problem with some people’s browsers?  Why can’t people continue the thread instead of splintering it into another category?  It’s really irritating, especially since my browser is slow and so the extra scrolling, guessing if the discussion is a continuation or new takes a lot of time and money. basically, I’m otta here.  Too slow. Best, AD Share what you know. Learn what you don’t.

Response:

Actually, a lot of your problem is your browser. Sure, people should be careful not to splinter threads, but a good browser will put most of that back where it goes. I see that you use Netscape3.01 Gold and Windows 95. Chances are that you have room on your hard drive for Agent, which will solve most of your problems. I used to get irritated at the same thing. Keith – Hide quoted text — Show quoted text – Maybe it’s me on effexor withdrawal, but the proliferation of these multiple threads sucks.  Is there a problem with some people’s browsers? Why can’t people continue the thread instead of splintering it into another category?  It’s really irritating, especially since my browser is slow and so the extra scrolling, guessing if the discussion is a continuation or new takes a lot of time and money. basically, I’m otta here.  Too slow. Best, AD Share what you know. Learn what you don’t.

Response:

Question:

In article <376E48A7.D623C…@primetimevisions.com

, "Nicholas S.-Roy"

<n….@primetimevisions.com

writes: I went to a cottage this weekend, and only knew 2 people on almost 10. Anyways it was great, and I’ve never been this social in my life. The Paxil seems to be doing more everyday. I talked to everyone, wasn’t shy, helped around, etc… It just felt really great not to be the outsider looking at the other people having fun.

Hi Nick, I had a pretty social weekend too. (for me)  What a world of difference it makes when you’re on the right meds : ) Each day, I feel a little better. Pam

Response:

What pink pills? Where can I get some? Nicholas S.-Roy <n….@primetimevisions.com

wrote in message

news:376EBB14.77C7EA34@primetimevisions.com… – Hide quoted text — Show quoted text -

thanks. although it’s only thanks to the little pink pills. sCOOTer wrote: In article <376E48A7.D623C…@primetimevisions.com, "Nicholas S.-Roy" <n….@primetimevisions.com wrote: I went to a cottage this weekend, and only knew 2 people on almost 10. Anyways it was great, and I’ve never been this social in my life. The Paxil seems to be doing more everyday. I talked to everyone, wasn’t shy, helped around, etc… It just felt really great not to be the outsider looking at the other people having fun. Nicholas: I hope we can say about you, as an SPic, "another one bites the dust." Pete

Response:

Paxil – Hide quoted text — Show quoted text -JimiJames wrote:

What pink pills? Where can I get some? Nicholas S.-Roy <n….@primetimevisions.com wrote in message news:376EBB14.77C7EA34@primetimevisions.com… thanks. although it’s only thanks to the little pink pills. sCOOTer wrote: In article <376E48A7.D623C…@primetimevisions.com, "Nicholas S.-Roy" <n….@primetimevisions.com wrote: I went to a cottage this weekend, and only knew 2 people on almost 10. Anyways it was great, and I’ve never been this social in my life. The Paxil seems to be doing more everyday. I talked to everyone, wasn’t shy, helped around, etc… It just felt really great not to be the outsider looking at the other people having fun. Nicholas: I hope we can say about you, as an SPic, "another one bites the dust." Pete

Response:

- Hide quoted text — Show quoted text -

  The physicians have given me zoloft + xanax then prozac.  Xanax was horrible…I don’t know how it helps anyone.  The zoloft and prozac were similar in effect…made me feel more content and made me much easier to get along with.  I didn’t want to be content or congenial, though.  I am panting to be more comfortable in college…that’s all.  The only relationships that I want are ones in which I am idolized as the enigma that I will always be, whether real or imagined.  Doesn’t it make any of you feel empty to act like everyone else?  I believe that if I weren’t shy, then I would be suicidal.  The biggest obstacle is the feeling that society is attempting to change me, and this becomes especially evident in college.  Their attempts wouldn’t be distressing if I wasn’t so sensitive to disapprobation…I want to be liked…not actually liked, too spiritless, but adored, envied, venerated, aggrandized…I don’t want to change.  The kind of counseling that I am getting isn’t helping, because I struggle with imagining that anyone really understands me…not because I’m too exceptional to be understood…because I have a distorted way of expressing myself.  No offense, but it seems to me that even doctors of the mind are easily misled…One must diffuse what I am saying to get to what is genuinely there.  I suppose I am expecting them to read my mind…after all the path from there to here is devious, and I’m not figuring it out.  I am mentioning all of this, because most of you talk about a manner of progress that is completely dissimilar to what I imagine for myself.  Anyway, we’re all just people experiencing the same symptoms, spawned from varying origins, induced by whatever, with different motivations, resulting in this…however you want to think of it.  Also, I felt like being opinionated and declaring that I hate mind playing drugs….the right ones, the wrong ones, the ones that work, the ones that don’t…any of them.  The ones that play in the pain region of your brain (no one expects me to know the names of all of these chemicals, regions, nerve transmitters, right? is it with the prostaglandins…I don’t know.) and other similar places don’t offend me that much….it’s just those ones that play in your  serotonin governors, emotional signals, GABAs, monoamine oxidase, whatever.  I’m not denying these drugs’ rights to excitement…They’re just uninvited right now.  Gotta be elaborate about it, y’know.

Leiliane

Response:

That good hey.. — ========= Russ. "Is this heaven?" ========= Nicholas S.-Roy <n….@primetimevisions.com

wrote in message

news:376F8854.8275E8F8@primetimevisions.com… – Hide quoted text — Show quoted text -> Paxil > JimiJames wrote: > > What pink pills? Where can I get some? > > Nicholas S.-Roy <n….@primetimevisions.com

wrote in message

> > news:376EBB14.77C7EA34@primetimevisions.com… > > > thanks. > > > although it’s only thanks to the little pink pills. > > > sCOOTer wrote: > > > > In article <376E48A7.D623C…@primetimevisions.com>, "Nicholas S.-Roy"

<n….@primetimevisions.com wrote: I went to a cottage this weekend, and only knew 2 people on almost

10.

Anyways it was great, and I’ve never been this social in my life.

The

Paxil seems to be doing more everyday. I talked to everyone, wasn’t shy, helped around, etc… It just felt really great not to be the outsider looking at the

other

people having fun. Nicholas: I hope we can say about you, as an SPic, "another one bites the

dust."

Pete

Response:

yup, I’ve met 3 girls since I’m on it, hehe – Hide quoted text — Show quoted text -JimiJames wrote:

That good hey.. — ========= Russ. "Is this heaven?" ========= Nicholas S.-Roy <n….@primetimevisions.com wrote in message news:376F8854.8275E8F8@primetimevisions.com… Paxil JimiJames wrote: What pink pills? Where can I get some? Nicholas S.-Roy <n….@primetimevisions.com wrote in message news:376EBB14.77C7EA34@primetimevisions.com… thanks. although it’s only thanks to the little pink pills. sCOOTer wrote: In article <376E48A7.D623C…@primetimevisions.com, "Nicholas S.-Roy" <n….@primetimevisions.com wrote: I went to a cottage this weekend, and only knew 2 people on almost 10. Anyways it was great, and I’ve never been this social in my life. The Paxil seems to be doing more everyday. I talked to everyone, wasn’t shy, helped around, etc… It just felt really great not to be the outsider looking at the other people having fun. Nicholas: I hope we can say about you, as an SPic, "another one bites the dust." Pete

Response:

OK, I’ve heard enough I’m getting some of that stuff — ========= Russ. "Is this heaven?" ========= Nicholas S.-Roy <n….@primetimevisions.com

wrote in message

news:3770E63E.D81E16DE@primetimevisions.com… – Hide quoted text — Show quoted text -> yup, I’ve met 3 girls since I’m on it, hehe > JimiJames wrote: > > That good hey.. > > — > > ========= > > Russ. > > "Is this heaven?" > > ========= > > Nicholas S.-Roy <n….@primetimevisions.com

wrote in message

> > news:376F8854.8275E8F8@primetimevisions.com… > > > Paxil > > > JimiJames wrote: > > > > What pink pills? Where can I get some? > > > > Nicholas S.-Roy <n….@primetimevisions.com

wrote in message

> > > > news:376EBB14.77C7EA34@primetimevisions.com… > > > > > thanks. > > > > > although it’s only thanks to the little pink pills. > > > > > sCOOTer wrote: > > > > > > In article <376E48A7.D623C…@primetimevisions.com>, "Nicholas > > S.-Roy" > > > > > > <n….@primetimevisions.com> wrote: > > > > > > > I went to a cottage this weekend, and only knew 2 people on almost

10. Anyways it was great, and I’ve never been this social in my

life.

The Paxil seems to be doing more everyday. I talked to everyone, wasn’t shy, helped around, etc… It just felt really great not to be the outsider looking at

the

other people having fun. Nicholas: I hope we can say about you, as an SPic, "another one bites the dust." Pete

Response:

I went to a cottage this weekend, and only knew 2 people on almost 10. Anyways it was great, and I’ve never been this social in my life. The Paxil seems to be doing more everyday. I talked to everyone, wasn’t shy, helped around, etc… It just felt really great not to be the outsider looking at the other people having fun.

Response:

I went to a cottage this weekend, and only knew 2 people on almost 10. Anyways it was great, and I’ve never been this social in my life. The Paxil seems to be doing more everyday. I talked to everyone, wasn’t shy, helped around, etc… It just felt really great not to be the outsider looking at the other people having fun.

That’s tight.  I’m happy for you.  Hope it lasts. ~ "No culture has a monopoly on beauty or value… Just as no religion has a monopoly on truth."  -Voltaire

Response:

In article <376E48A7.D623C…@primetimevisions.com

, "Nicholas S.-Roy"

<n….@primetimevisions.com

wrote: I went to a cottage this weekend, and only knew 2 people on almost 10. Anyways it was great, and I’ve never been this social in my life. The Paxil seems to be doing more everyday. I talked to everyone, wasn’t shy, helped around, etc… It just felt really great not to be the outsider looking at the other people having fun.

Nicholas: I hope we can say about you, as an SPic, "another one bites the dust." Pete

Response:

thanks. although it’s only thanks to the little pink pills. – Hide quoted text — Show quoted text -sCOOTer wrote:

In article <376E48A7.D623C…@primetimevisions.com, "Nicholas S.-Roy" <n….@primetimevisions.com wrote: I went to a cottage this weekend, and only knew 2 people on almost 10. Anyways it was great, and I’ve never been this social in my life. The Paxil seems to be doing more everyday. I talked to everyone, wasn’t shy, helped around, etc… It just felt really great not to be the outsider looking at the other people having fun. Nicholas: I hope we can say about you, as an SPic, "another one bites the dust." Pete

Response:

Nicholas S.-Roy <n….@primetimevisions.com

wrote in message

news:376EBB14.77C7EA34@primetimevisions.com…

thanks. although it’s only thanks to the little pink pills.

That’s good enough.

Response:

true – Hide quoted text — Show quoted text -Hunter wrote:

Nicholas S.-Roy <n….@primetimevisions.com wrote in message news:376EBB14.77C7EA34@primetimevisions.com… thanks. although it’s only thanks to the little pink pills. That’s good enough.

Response:

Great! I’m so happy for you. – Hide quoted text — Show quoted text -MzPami wrote:

In article <376E48A7.D623C…@primetimevisions.com, "Nicholas S.-Roy" <n….@primetimevisions.com writes: I went to a cottage this weekend, and only knew 2 people on almost 10. Anyways it was great, and I’ve never been this social in my life. The Paxil seems to be doing more everyday. I talked to everyone, wasn’t shy, helped around, etc… It just felt really great not to be the outsider looking at the other people having fun. Hi Nick, I had a pretty social weekend too. (for me)  What a world of difference it makes when you’re on the right meds : ) Each day, I feel a little better. Pam

Response:

Question:

Hi.  I’ve been on Prozac fort Attention Deficit Disorder for about two months now.  I recently started having problems with insomnia. My Psychiatrist started me on trazodone (Desyrel) in the evenings to help me sleep, but I seem to be getting some bad side effects from it (indigestion, trouble concentrating, and sexual problems). Here’s my question.  It seems like Psychiatrists have a reluctance (justified I’m sure) to prescribe hypnotics or other strong sleep medications to overcome the insomnia that is fairly common with Prozac.  Does anyone out there know what is used apart from the other anti-depressants (e.g., trazodone and amitriptyline)? Has anyone actually had their Psychiatrist prescribe them Halcion or something similar? Would over-the-counter sleep medications do any good? Since I am being treated for ADD, any drugs that take a long time to wash out, or leave my mind feeling "dull" are out of the question. As always, thanks for any and all help. — | Richard S. Smith  | PROGRESS(tm) 4GL Developer | Monrovia, California  |

Response:

: Hi.  I’ve been on Prozac fort Attention Deficit Disorder for about : two months now.  I recently started having problems with insomnia. : My Psychiatrist started me on trazodone (Desyrel) in the evenings to : help me sleep, but I seem to be getting some bad side effects from : it (indigestion, trouble concentrating, and sexual problems). : Here’s my question.  It seems like Psychiatrists have a reluctance : (justified I’m sure) to prescribe hypnotics or other strong sleep : medications to overcome the insomnia that is fairly common with : Prozac.  Does anyone out there know what is used apart from the : other anti-depressants (e.g., trazodone and amitriptyline)? : Has anyone actually had their Psychiatrist prescribe them Halcion : or something similar? : Would over-the-counter sleep medications do any good? : Since I am being treated for ADD, any drugs that take a long time to : wash out, or leave my mind feeling "dull" are out of the question. : As always, thanks for any and all help. : — : | Richard S. Smith  | PROGRESS(tm) 4GL Developer | Monrovia, California  | i’ve found a good drink helps the most. i can’t stand the feeling of sleeping pills after one night of them. drink in moderation

Response:

: Hi.  I’ve been on Prozac fort Attention Deficit Disorder for about : two months now.  I recently started having problems with insomnia. By the time insomnia kicks in with any of these drugs, chances are the good effects are diminishing too. I question the long term use period. Halcion would give you a double whammy. It might work one or two nights a week and set you up for some unexpected side effects. If you have no physical problems, consider exercise and walks and interventionist type psychologists. Avoid Freudians. —                                              And this is where                                              they spin gold into                                              straw.

Response:

: By the time insomnia kicks in with any of these drugs, chances are the : good effects are diminishing too. I question the long term use period. What is long term use?  I was on Prozac for 2+ years before my body started getting used to it and I had to try another SRI.  The good effects started 1 1/2 days after starting it, and I never had what I would characterize as insomnia. : If you have no physical problems, consider exercise and walks and : interventionist type psychologists. Avoid Freudians. Too bad psychologists have never been proven to work.  The changes I had in 1 1/2 days could not have been wrought by psychologists in 20 years.

Response:

Too bad psychologists have never been proven to work.  The changes I had in 1 1/2 days could not have been wrought by psychologists in 20 years.

Hehehee.  Thank you Jeanne, I enjoyed that.  No offense intended to any professional people out there (and it certainly took me more than 1 1/2 days to see effects from my first antidepressant), but I know exactly what you mean.  :) lilo

Response:

               ….. The best drug yet for add. Hits all 3 brain                interactions. seriton, … Helps me concentrate without                the stimatues like dexadrine, ritalitin,….                 Effexor FAQ  Version 1.0  3 March 1994                                   Index. 1. What is Effexor 2. How does Effexor differ from other antidepressants? 3. What kinds of depression can be treated with Effexor? 4. What are the side-effects of Effexor? 5. Which side effects force people to stop taking Effexor? 6. Are there any special hazards for people with bipolar disorder? 7. Does Effexor interact with other medications? 8. Does Effexor interact with alcohol? 9  Is Effexor safe for a woman who is pregnant, about to become pregnant,    or nursing an infant? 10. How is treatment with Effexor initiated? 11. What is the usual final dose of Effexor? 12. Are there withdrawal effects if Effexor is suddenly discontinued? 13. Is Effexor toxic if an overdose is taken? 14. What will Effexor cost? 15. When will Effexor be available? 16. Additions and corrections. 1. What is Effexor         Effexor is a new antidepressant with a novel chemical structure.  The chemical structure of Effexor does not resemble those of any currently used antidepressants.  Effexor is not an MAO inhibitor 2. How does Effexor differ from other antidepressants?         Effexor seems to have the relative freedom from side-effects associated with the SSRIs [fluoxetine (Prozac), sertraline (Zoloft), paroxetine (Paxil), fluvoxamine (Luvox)] and the impact on both the serotonin and norepinephrine associated with the tricyclic antidepressants (amitriptyline (Elavil), inipramine (Tofranil) etc.).  It is hypothesized that the action of the Effexor molecule upon both serotonin and norepinephrine will cause Effexor to be a successful antidepressant for some people who have not responded to treatment with SSRIs. 3. What kinds of depression can be treated with Effexor?         While the pre-marketing studies were restricted to patients with a DSM-III-R diagnosis of Major Depressive Disorder (with or without melancholia), it is to be expected that Effexor will be prescribed for patients with Dysthymia, Major Depression, and Bipolar Disorder.         Although here have been no published studies on the use of Effexor for the treatment of children and adolescents with depression, it can be expected that the drug will be prescribed for depressed children and adolescents.         No special problems were encountered when Effexor was prescribed for elderly people with depression.         While Effexor was only studied for periods of administration of up to 6-weeks, it is to expected that patients with long-standing depressions will take the drug for longer periods of time. 4. What are the side-effects of Effexor?         The most common side-effects and the percentage of people reporting them during clinical trials are:                                 Nausea                  37%                                 Headache                25%                                 Sleepiness              23%                                 Dry mouth               22%                                 Dizziness               19%                                 Insomnia                18%                                 Constipation            15%                                 Nervousness             13%                                 Fatigue                 12%                                 Sweating                12%                                 Decreased appetite      11%                                 Male sexual dysfunction 12%                                 Female sexual                                           Dysfunction    2% 5. Which side effects force people to stop taking Effexor?         In the premarketing studies  19% (537 / 2897) of depressed patients taking Effexor discontinued the medication because of side-effects. The side effects and the percentages of total patients who dropped out for each are:                                 Nausea                  6%                                 Sleepiness              3%                                 Insomnia                3%                                 Dizziness               3%                                 Male sexual dysfunction 3% *                                 Headache                2%                                 Nervousness             2%                                 Anxiety                 2%                                 Dry mouth               2%                                 Fatigue                 2%                                 Sweating                2%                                            * % of men 6. Are there any special hazards for people with bipolar disorder?         As with other antidepressants, people with bipolar disorder who are not being treated with a mood regulator such as lithium, valproate (Depakote), or carbamazepine (Tegretol), may be pushed into a manic episode when treated with Effexor. 7. Does Effexor interact with other medications?         Lithium – No interaction         Diazepam (Valium) – No interaction         Cimetidine (Tagamet) – Slight increase in blood level of         Effexor’s active metabolite.  Not of clinical significance.         Fluoxetine (Prozac) – Significant increase in the concentration         of Effexor and its active metabolite.  Potential for increased side-         effects. 8. Does Effexor interact with alcohol?         Although Effexor has not been found to increase the impairment of cognitive or motor skills caused by alcohol, the manufacturer warns against drinking while taking Effexor. 9 Is Effexor safe for a woman who is pregnant, about to become pregnant,   or nursing an infant?         There is no data to establish the safety of Effexor for the fetus   or nursing infant. 9. How is treatment with Effexor initiated?         The usual starting dose of Effexor is 75 mg a day taken in two or three divided doses with food (to minimize nausea).  If higher doses are needed, the dose should not be increased more rapidly than 75 mg every 4 days. 10. What is the usual final dose of Effexor?         While doses up to 375 mg per day are approved by the FDA, some severely depressed patients have been treated with higher doses.  Most depressed people have been found to respond to doses under 300 mg per day. 11. Are there withdrawal effects if Effexor is suddenly discontinued?         Effexor should be discontinued gradually over at least 2-weeks.  If Effexor  suddenly discontinued, a withdrawal syndrome involving fatigue, nausea, dizziness, headache, insomnia, and nervousness, may develop. 12.  Is Effexor toxic if an overdose is taken?         Fourteen overdoses of Effexor have been reported.  In some cases Effexor was taken along with alcohol and/or other medications.  All individuals who took an overdose recovered without sequelae. 13. What will Effexor cost?         Effexor will be supplied in tablets ranging from 25 to 100 mg in strength.  The 25 mg tablets cost pharmacies nearly as much as the 100 mg tablets.  It is expected that all strengths of Effexor will be sold for between $1.00 and $1.50 per tablet. 14. When will Effexor be available?         A few psychiatrists have been given small supplies of Effexor. It is expected that Effexor will be widely available by the first week of April of 1994. 15. Additions and corrections.         This FAQ was prepared by Ivan K. Goldberg, MD.  Please address —                                                                 \\         ||                             Ivan Goldberg, MD                 ~        || ||    Voice Mail = 212-744-1846      ||      Fax = 212-737-0473           || || Snail Mail = NY Psychopharmacologic Inst. 1346 Lexington Ave NYC 10128 || : Hi.  I’ve been on Prozac fort Attention Deficit Disorder for about : two months now.  I recently started having problems with insomnia. : My Psychiatrist started me on trazodone (Desyrel) in the evenings to : help me sleep, but I seem to be getting some bad side effects from : it (indigestion, trouble concentrating, and sexual problems). : Here’s my question.  It seems like Psychiatrists have a reluctance : (justified I’m sure) to prescribe hypnotics or other strong sleep : medications to overcome the insomnia that is fairly common with : Prozac.  Does anyone out there know what is used apart from the : other anti-depressants (e.g., trazodone and amitriptyline)? : Has anyone actually had their Psychiatrist prescribe them Halcion : or something similar? : Would over-the-counter sleep medications do any good? : Since I am being treated for ADD, any drugs that take a long time to : wash out, or leave my mind feeling "dull" are out of the question. : As always, thanks for any and all help. : — : | Richard S. Smith  | PROGRESS(tm) 4GL Developer | Monrovia, California  | — Scott Onofrio                            LaserJet IHV Developer Group

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Response:

(Jeanne Guidry) writes:

I just started Prozac in conjuction with Cylert and have noticed no effects after a week; moreover, my psyc said that the clinical effects probably won’t be evident for at least a month, although I might see some changes, most notably side effects, earlier.  So far, so good–no headaches, insomnia, etc. But then again, my biochem is probably different as Ritalin had little clinical effect on me.

Response: